- Singed was designed by both Ezreal and Guinsoo.
- According to Udyr, Singed was the first ever champion to be created in the game.
- Singed is possibly a reference to the werewolf chemist in the first Underworld movie.
- Singed's lore shares some similarities with the chemist Shimon Haber. There are also similarities in the ethical implications of both their work.
- Singed was one of the champions chosen for the Noxian pool available during the Ionia vs. Noxus match. He was one of the selected champions.
- Singed's dance is the "Jump on It" dance from The Fresh Prince of Bel-Air.
- Even though Singed's Poison Trail cloud appear to expand as they fade, the area affected by the poison does not actually increase.
- Singed's line, "To shake, or not to shake," is a play on, "To be, or not to be," a famous quote from William Shakespeare's play Hamlet.
- Singed's joke, "Shaken, not stirred." is a reference to a famous quote of James Bond, a fictional British secret agent.
- Riot Squad Singed was normally only available via promotional codes. It was first gifted at the Gamescom 2010 and other events that Riot Games attends to, such as PAX and E3. However, the skin has now been replaced with the K-9 Nasus skin.
- Taric is on the bottle of Surfer Singed splash art, complete with surfer shades.
- The bottle is labeled "Taric's Tropical Tan".
- Mad Scientist Singed is based on the stereotypical mad scientist.
- Augmented Singed is possibly a reference to Bane from the Batman franchise.
- The skin's release date is also very close to the premiere of the new Batman movie, The Dark Knight Rises, in which Bane is the main villain.
- Singed was Warwick's apprentice in alchemy, until his master was transformed by the incomplete potion he consumed.
- Singed invented the toxic weapon used on Master Yi's home village. The remains of the village were so horrific that it remains a festering scar on Ionian history. To this day, no Ionian will ever publicly speak of what occurred.
- During an Ionian ambush on Noxian troops, Singed launched a barrage of biochemical terror on both forces. Riven witnessed as around her Ionian and Noxian alike fell victim to an unspeakably gruesome fate.
- Singed and Blitzcrank are on unfriendly terms with one another.
- Singed is commonly teammates with his fellow Zaunites, Warwick and 20px Dr. Mundo, on the Twisted Treeline.
- In the Navori Province of Southern Ionia, Singed was charged with the extermination of an unexpected giant rat infestation. Some suspect that Twitch may have been involved in the rodent invasion.
- Singed is a business partner of Gragas, responsible for supplying him with brewing machinery and hardware.