- Sion was designed by Ezreal (person).
- Sion is voiced by J.S. Gilbert, Who also voices Battlecast Prime Cho'Gath, 20px Dr. Mundo and Gragas.
- Sion's Dance is reminiscent of "Moskau" by Dschinghis Khan. A side-by-side comparison can be seen here .
- Sion was one of the first six characters designed, along with Singed, Annie, Sivir, 20px Twisted Fate and Lee Sin ,
- Sion was one of the champions available for the Noxian pool during the Ionia vs. Noxus match, and was one of the selected champions.
- Feel No Pain was possibly taken from the Warhammer 40,000 table top game, where it is a special rule that gives units a chance to ignore wounds.
- Many of Sion's quotes are based on old Arnold Schwarzenegger movies.
- Sion's quote "Get on my Chopper!" is a reference to Arnold Schwarzenegger's famous line "Get to the Chopper!" from the movie Predator
- Sion's quote "Who is your summoner, and what does he do?" is a reference to Kindergarden Cop.
- Sion's taunt is a reference to an exchange in the 1982 movie Conan the Barbarian between the Mongol General and Conan.
- Sion's joke is a reference to Dem Bones.
- Hextech Sion is a reference to the Terminator franchise.
- Hextech Sion's robotic eye is on the right of the original artwork, but on the left in the Chinese artwork.
- Barbarian Sion is a reference to the character Conan the Barbarian.
- Sion's character model now shows him wielding a double-bladed axe, as he does in his Warmonger and Barbarian skins, rather than the classic single-bladed axe that still currently appear in both of his classic skin artworks.
- Lumberjack Sion skin is a reference to Paul Bunyan, with Unchained Alistar as the reference to Babe, the Blue Ox.
- Lumberjack Sion may also be a refernce to, though less likely, Mark Kaminsky - character from movie Raw Deal, played by Arnold Schwarzenegger.