- Lee Sin was designed by Coronach.
- Lee Sin is voiced by David Wenham.
- Lee Sin's name is a homophone of the word "listen."
- His self-immolation from the lore is a reference to the real life monk who publicly set himself on fire. He did this as an act of protest against the persecution of Buddhism in South Vietnam.
- Lee Sin is the first champion to feature two champion spotlights, a real one and a fake one for April Fool's.
- Lee Sin is the first champion to use energy that is not a ninja. Though, similar to the other ninjas, he is a champion that hails from Ionia.
- Lee Sin is one of only four champions to have more than 4 skills, the other being Nidalee, Jayce and Elise.
- Lee Sin is the first monk type champion announced but the second to be released after Udyr.
- Lee Sin is the only allegedly cancelled Champion to be introduced to the game under his original name.
- Lee Sin was a cancelled Champion that got brought back by community popularity and support.
- Lee Sin's dance style is referenced to one of 'Mighty Steel Legs' moves in the movie Shaolin Soccer. A side-by-side comparison can be seen here.
- For April Fool's, the original Classic skin artwork used to have the deceased champion Urf, the Manatee, who could be seen at the bottom left of the artwork.
- Traditional Lee Sin resembles how he looked before his official release (seen in the second official trailer). Click here.
- Dragon Fist Lee Sin (Lunar Revel 2012 event release) skin is a tribute to Bruce Lee, the famed martial artist/actor of 1970's action movies. The skin seems to be specifically referencing his trademark look first seen in Enter the Dragon.
- Muay Thai Lee Sin was created to celebrate the launch of League of Legends in Thailand and pays homage to Muay Thai, a combat sport native to the country.
- Muay Thai Lee Sin is the third non-legendary skin to have a different dance animation from the original skin, prior being Jurrasic Cho'Gath and Dynasty Ahri.
- Muay Thai Lee Sin is very similar to Sagat's outfit from the Street Fighter fighting game series.
- Lee Sin was once a summoner-in-training at the League, before committing a devastating incident which left him with profound guilt. After the devastating incident, he traveled to the Shojin Monastery in Ionia in order to repent, becoming a brethren to the monks there.
- Lee Sin's former mentor was High Councilor Reginald Ashram, the first leader of the League.
- Lee Sin has a sister from the now liberated province of Galrin.
- Lee Sin did an interview with L. B. Briskes on a raft over Lake Contemplation.