- The word "Shen" literally means "God" in Chinese. The word "慎" (meaning caution), with same pronouciation, is used on Chinese clients.
- Shen is currently the only Ninja to not have his face revealed in a skin. Kennen's Karate & M.D. skins and Akali's Soccer, Nurse, & Blood Moon skins, respectively, reveal their faces.
- Shen was designed by Guinsoo. Appropriately enough, Shen chants "Guinsoo" when using Stand United.
- Shen is voiced by Keith Silverstein.
- Shen was one of the champions chosen for the Ionian pool available during the Ionia vs. Noxus match. However, he was the ban choice by Noxus.
- Shen carries dual Ninjatō. This could be a reference to Leonardo from Teenage Mutant Ninja Turtles who wields dual ninjaken. Both are leaders of their teams and share the color blue.
- Shen has a strong resemblance to Joe Musashi, the ninja from the Sega game series Shinobi. The two ninjas also share the same walk animation and dash.
- Shen's Vorpal Blade ability is a reference to Lewis Carroll's poem, Jabberwocky.
- Shen's dance bears a resemblance to the martial art commonly known as Tai Chi.
- "If light travels so fast, how come it's never caught a ninja?" is a direct reference to the Ask A Ninja web series.
- You're already dead, you just haven't caught up yet. is a reference to Kenshiro from the Fist of the North Star (Hokuto no Ken in original Japanese) franchise.
- Shen shares a quote with Zed: "Without a sound."
- Yellow Jacket Shen resembles Scorpion and Frozen Shen resembles Sub-Zero from the Mortal Kombat franchise. He is also currently the only champion to have multiple skins that, with no speculation required, reference the same origin.
- Surgeon Shen skin is a posible reference to The Adventures of Dr. McNinja which protagonist is a ninja who decided to be a doctor.
- In the Blood Moon Shen skin, he wears a Hannya Mask to cover his face, making him the "dark spirit" mentioned here.
- Shen is a member of the Kinkou Order along with Akali and Kennen. The three shadow warriors work together in order to preserve the balance in Valoran.
- Shen was the rival of Zed a former disciple of the Kinkou Order, who was banished after he used forbidden techniques to defeat Shen. Zed later returned and killed Shen's father.
- Shen and his fellow ninjas are at war with Zed and his Order of Shadows