- Darius was designed by CertainlyT.
- Darius' name derives from the Persian word "Dariush", which means "Kingly".
- Darius is the first champion to have a special animation while using Recall or Teleport in which he lifts his axe upward and looks up.
- Darius and his brother Draven are the first related champions to be released back to back.
- Both of Darius' jokes have him trying to spin while shouting "Noxus!" as a reference to Garen and the popular "Spin-To-Win" joke. However, Darius has difficulty performing the move and, in one of said jokes, wonders how Garen does it.
- In Darius' classic splash art, Beatrice ( Swain's raven) appears in the battlefield.
- Bioforge Darius shares the theme with Augmented Singed.
- Darius has an (currently) unreleased skin called Norse King Darius.
- When his Ultimate, Noxian Guillotine, is used, his model will change to be spattered with blood.
- Darius has formed an alliance with Jericho Swain, the Master Tactician, seeing him as a leader with the mind and determination to bring Noxus to glory. With Swain, Darius works to unite the nation behind his vision of true Noxian strength. However, it is unknown whether Darius knows about Swain's past with the Black Rose organization.
- Darius is Draven's older brother. The two together are known as "The Blood Brothers".