- Galio was designed by rjcombo.
- Galio is voiced by David Lodge, Who also voices Skarner.
- His /dance is the same as Belle and the Beast performed in the Beauty and the Beast from Walt Disney. Galio imitates the dance of the male lead.
- Enchanted Galio is a possible reference to Chernabog from the Disney film Fantasia.
- Hextech Galio has some resemblance to The Iron Giant from the eponymous Warner Bros movie, and some resemblance to the characters from the movie "9".
- Hextech Galio could be a reference to Clank from the Ratchet and Clank series.
- Commando Galio is a reference to the Imperial Guard of the Warhammer 40,000 series.
- Galio's Gatekeeper skin is one of the legendary skins at 1820RP which was released on April 23, 2012.
- His skin resembles Hellboy, a hero from Dark Horse Comics, due to his red skin, giant fists, demon horns, and chonmage hairstyle. His wings are the only contradiction to the likeness of Hellboy.
- The runes that mark the arms, also mark the cards of Underworld Twisted Fate. Showing a link between the two skins, as Galio guards the gate to the underworld.
- In early 2012, Galio's classic artwork, as well as those of Alistar, Fiddlesticks, and Malzahar had their artwork replaced with the Chinese Classic artworks. Galio's classic artwork was changed again since then, however.
- Galio's Gatekeeper skin is the 3rd non-comical legendary skin. the 1st belonging to Tryndamere and the 2nd to Vladimir
|Gatekeeper Galio's Theme|