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Conqueror or Press the Attack cannot be gained as the first keystone.
- The Exposed debuff from Press the Attack will increase the damage of any subsequent damaging Keystones by 8% − 12% (based on level), so long as the Keystone is triggered prior to the Exposed debuff expiring.
- The Exposed debuff from
- Omnistone can still grant Predator if the user has Magical Footwear but has not been granted the boots yet.
- This can only happen once, as once Omnistone refills its table of Keystones, Predator can no longer be rolled if the owner does not have boots in their inventory.
- This can also happen to Cassiopeia, who can neither purchase boots, nor can she take Magical Footwear.
- This can only happen once, as once
"Smart" Keystone Chances
- "Smart" selection takes place before Omnistone rolls its table of Keystones; if an ideal situation is found it will have an 8 - 15% increased chance to roll the relevant Keystone.[1] If you would otherwise not roll a relevant Keystone due to it being removed from the table, Omnistone will refill its table of Keystones, and grant you the relevant Keystone.
- "Smart" selection cannot grant you the same Keystone consecutively.
- It is however possible to "chain" Keystones through "Smart" selection, where you can obtain the same smart selected Keystone several times in a short span of time. For example, due to "Smart" selection, it is possible to roll: "Smart" Keystone > Grasp of the Undying > "Smart" Keystone > Fleet Footwork > "Smart" Keystone; where each of the "Smart" Keystones are the exact same Keystone.
- It is however possible to "chain" Keystones through "Smart" selection, where you can obtain the same smart selected Keystone several times in a short span of time. For example, due to "Smart" selection, it is possible to roll:
- A specific Keystone will be given to the user under many circumstances fit for the gameplay scenario. The following have an increased chance to be given:
- Conqueror when the user and other enemy champions have high health, further increased chance for melee champions.
- Fleet Footwork if the user is low health and below level 9.
- Dark Harvest when near low health enemy champions.
- Hail of Blades when near low health enemy champions and building attack speed or attack damage.
- Predator when not near enemy champions, and less likely to get it when in combat with nearby enemy champions.
- Summon Aery if the user has healing and shielding power and are near a low health ally who is in combat.
- This includes the healing and shielding power given by Revitalize.
- This includes the
- Glacial Augment if the user owns an active item with a slow that is off cooldown.
- If you are a Melee champion, the bonuses from Conqueror and Lethal Tempo last longer than the cooldown of Prototype: Omnistone, which can affect "Smart" selection, as well as empower other keystones.
- If you are an AD champion, stacks of Conqueror can increase the likelihood of rolling Hail of Blades. Likewise, the bonus Attack Speed gained from Lethal Tempo can also increase the likelihood of rolling Hail of Blades.
- Additionally, the Adaptive Force gained from Conqueror increases the potency of other Keystones that scale with Adaptive Force, such as Arcane Comet, in addition to Healing for the damage dealt.
- If you are an
Dark Harvest Soul Bonuses
- The following Keystones have their stats enhanced based on the number of Dark Harvest stacks. Soul bonuses are relative to the damage per stack of Dark Harvest per map, meaning it can be lower or higher depending on the mode.[2] (The following are based on Summoner's Rift, with Dark Harvest dealing 5 damage per soul):
- Conqueror gains (+ 2.5% per Soul) more adaptive force.
- Fleet Footwork gains (+ 5 per soul) healing and (+ 5% per soul) bonus movement speed when activated.
- Lethal Tempo gains (+ 5% per Soul) bonus attack speed when activated.
- Press the Attack gains (+ 10 per soul) adaptive damage when activated.
- Notably, the damage from Exposed doesn't increase.
- Electrocute gains (+ 5 per soul) adaptive damage when activated.
- Hail of Blades gains (+ 5% per soul) bonus attack speed when activated.
- Predator gains (+ 5 per soul) adaptive damage.
- Notably, no bonus movement speed is gained on activation.
- As of V10.12, Predator is not scaling with stacks of Dark Harvest.(note)
- Arcane Comet gains (+ 5 per soul) adaptive damage when activated.
- Phase Rush gains (+ 5% per Soul) bonus movement speed and slow resist when activated.
- It is possible to reach and exceed 100% slow resist, and thus become immune to slows.
- It is possible to reach and exceed 100%
- Summon Aery gains (+ 5 per soul) enemy adaptive damage or ally shielding when activated.
- Aftershock gains (+ 2.5% per Soul) bonus armor and armor scaling, (+ 2.5% per Soul) bonus magic resistance and magic resistance scaling, and (+ 3.75 per Soul) more magic damage.
- Resistance scaling increases multiplicatively.
- Grasp of the Undying gains (+ 3.33% per Soul) healing and damage per empowered attack, and also, (+ 5% per Soul) maximum health per stack, including ones previously gained.
- Glacial Augment gains (+ 2.5% per Soul) slow strength.
Strategy
Omnistone's best use scenario is not maximizing the potential of every keystone, but rather to dispense the keystones you use least effectively in order to gain access to your most efficient ones. As such, if there are keystones you can roll, but cannot dispense due to a champion's inherent kit design (e.g 
Karthus, or 
Anivia, whose kits do not allow much use of auto attacks), Omnistone is most likely to not be the best fit for you.
General tips:
- Some champions cannot dispense of Arcane Comet easily, such as Trundle, because they do not have any basic abilities that apply spell effects. It is advised to purchase items that trigger spell effects (such as Stridebreaker) to assist in applying these keystones.
- If you have a passive effect which's cooldown or power is improved by landing basic attacks, such as Aatrox's Deathbringer Stance or Vi's Denting Blows, rolling Lethal Tempo or Hail of Blades can help you lower their cooldown or apply the effect more frequently.
- Champions with attack resets, such as Jax's Empower or Camille's Precision Protocol can best make use of Hail of Blades and Press the Attack, as they can use their empowered auto attacks as a means to quickly dispense both keystones.
- The more immobilizing crowd control you have in your kit, the better you are at using Omnistone. This is because the longer a target is locked down, the easier it is to dispense a keystone on them, regardless of how optimal it may be. The same holds true if you have crowd control that lasts for a long duration, such as Morgana's Dark Binding.
- This makes Omnistone appealing on champions such as Nautilus, Leona, Skarner, Pyke, Sion, Sett, and Bard, as they all either have multiple sources of immobilizing crowd control, or they have crowd control that lasts for a long duration.
- This makes
- Smart Selection:
- Keystones that are rolled as a result of Smart Selection (such as Dark Harvest) refresh the table of keystones, allowing you to chain keystones.
- For example, with Dark Harvest or another Smart Selected keystone, it is possible to roll a series of keystones such as: Dark Harvest -> Conqueror -> Dark Harvest -> Grasp of the Undying -> Dark Harvest.
- For example, with Dark Harvest or another Smart Selected keystone, it is possible to roll a series of keystones such as:
- Keystones that are rolled as a result of Smart Selection (such as
- Glacial Augment can be dispensed with both a basic attack, and active items with a slow, meaning that champions who may not necessarily auto attack very often can purchase items such as Stridebreaker, Turbo Chemtank, Everfrost, or Randuin's Omen to utilize the keystone.
- Due to the increased likelihood of rolling Glacial Augment if you have an active item slow off cooldown, it is generally advised to take either Cosmic Insight or Approach Velocity in order to maximize its effectiveness.
- Due to the increased likelihood of rolling
- Revitalize's heal and shield power increases the likelihood of rolling Summon Aery, as its probability is increased based on your heal and shield power. Unless you are an Enchanter, or a champion who actively uses Revitalize to boost their innate or purchased sustain, such as Aatrox's Umbral Dash, it is generally advised to avoid taking this minor rune alongside Omnistone because of this.
If you are a 
melee champion:
- Due to the lack of target access that melee champions inherently have as a range class, maintaining your distance to increase the likelihood of rolling Predator will allow you to better access your targets, or to enhance any existing engage spells, such as Nunu's Biggest Snowball Ever! or Warwick's Infinite Duress.
- Conqueror's probability to be rolled is based on the percent current health of nearby enemies, which makes your likelihood of rolling Conqueror greatest in a teamfight.
- For melee champions, Prototype: Omnistone has a [5-3] second scaling cooldown. The following buffs persist long enough that they can help you proc other keystones, empower subsequent keystones, as well as impact Smart Selection:
- Conqueror
- If you are an AD champion, fully stacking Conqueror will increase the likelihood of rolling Hail of Blades.
- If you are an
- Lethal Tempo
- The buff can last up to 6 seconds after an initial delay, allowing to possibly dispense up-to 2 keystones during its duration.
- The boost in attack speed increases the likelihood of rolling Hail of Blades. As such, it is possible to obtain a minimum boost of up to 220% attack speed for 3 auto attacks, which can burst unsuspecting targets in a fight.
- This is especially beneficial for melee champions who build Critical Strike Chance, such as Tryndamere, Yasuo, and Yone, as with enough Critical Strike Chance, they can potentially critically strike 3 times in rapid succession.
- This is especially beneficial for melee champions who build
- Grasp of the Undying
- Glacial Augment*
- *If triggered by an active item with a slow.
If you are a 
ranged champion:
- The following keystones will empower any in-flight projectiles fired as a result of a basic attack, or a spell that applies On-Hit effects to apply relevant stacks, or proc relevant keystones:
- Conqueror
- Press the Attack
- Electrocute
- Phase Rush
- Glacial Augment
- Grasp of the Undying*
- *If fully stacked by the time the projectile is in mid-air.
- Aftershock*
- *If the in-flight projectile applies immobilizing crowd control, such as Twisted Fate's Gold Card.
- *If the in-flight projectile applies
- If you are a ranged champion with a global ability with a projectile, such as Ezreal's Trueshot Barrage, Senna's Dawning Shadow, or Draven's Whirling Death, an Omnistone-granted Predator can be cast while the spell is in-flight, allowing its next hit against a champion to apply the bonus damage.
- During Gangplank's Cannon Barrage, Predator can be cast, causing the next available tick of his ultimate to apply the bonus damage after the 0.25s delay.
- Likewise, rolling Arcane Comet or Dark Harvest empowers the in-flight projectile to immediately dispense the keystone (provided the conditions are met) upon the champion being hit by the spell.
- During
- Most Mage champions generally do not attack with enough frequency to efficiently dispense of auto attack based keystones. Those that do generally have some inherent interaction with auto attacks, such as Lux's Illumination, Twisted Fate's Stacked Deck, or Orianna's Clockwork Windup.
- Champions like the abovementioned can purchase Nashor's Tooth to further assist in dispensing of said keystones.
- Champions like the abovementioned can purchase
- For Marksman champions, Omnistone's efficiency relies on several factors:
- If you are primarily spell-focused, or use a large mixture of spells and auto attacks, such as Jhin, Senna, Kog'Maw, Varus, or Kai'Sa, it is best to quickly dispense of inefficient keystones such as Summon Aery and Predator by using your longer range abilities. This increases the likelihood of rolling much more efficient keystones, such as Hail of Blades, Electrocute, and Arcane Comet.
- Purchasing items such as Divine Sunderer or Essence Reaver is also advised for these types of champions when running Prototype: Omnistone, as they will be casting spells with a higher frequency than normal to dispense of keystones more rapidly.
- Purchasing items such as
- If you primarily rely on basic attacking to deal your damage, such as Vayne, Tristana, On-Hit or crit Varus/ Kog'Maw/ Senna, it is advised to save your abilities that apply spell damage to dispense of Arcane Comet. This is because these champions tend to cast their spells less frequently, or have less spells that apply spell effects, which is the only way Arcane Comet can be properly dispensed.
- It is also advised that these champions purchase either Guinsoo's Rageblade or Navori Quickblades (based on which type of build they are running), as Seething Strike and Deft Strikes can speed up the rate at which you activate Conqueror, which is generally a difficult keystone for marksmen to activate, due to its 12-stack requirement.
- It is also advised that these champions purchase either
- If you are primarily spell-focused, or use a large mixture of spells and auto attacks, such as
- If you are an Enchanter, or a Support champion with an ability that empowers allies, such as Nami, Sona, or Bard, it is advised to take Revitalize, as the increased heal and shield power boosts the likelihood that you will roll Summon Aery, whose shield is then boosted by the aforementioned rune.
Trivia
- The name "Kaleidostone" was the placeholder for this rune during the removal of Kleptomancy.
- WIth Prototype: Omnistone and enough Dark Harvest stacks, it is possible to achieve the absolute maximum Attack Speed cap of 90.00, utilizing Lethal Tempo or Hail of Blades.
- At level 18, ignoring Attack Speed gained per level, this would require a minimum bonus of 120000% Attack Speed on Maokai, or roughly 21820 Dark Harvest stacks, and a maximum bonus of 163000% Attack Speed on Rell, or roughly 29639 stacks of Dark Harvest.
- At level 18, ignoring
Media
Prototype: Omnistone with Precision
Prototype: Omnistone with Domination
Prototype: Omnistone with Sorcery
Prototype: Omnistone with Resolve
Patch History
- Removed: Can no longer gain Conqueror or Press the Attack as its first Keystone.
- Bug Fix: Champions may no longer trigger Grasp of the Undying several times in one rotation.
- Bug Fix: Omnistone-granted Predator now has a proper cooldown regardless of when the user upgrades its boots.
- Cooldown for melee champions reduced to 5 − 3 (based on level) seconds from 7 − 3 (based on level).
- Cooldown for ranged champions reduced to 9 − 7 (based on level) seconds from 11 − 7 (based on level).
- Now displays how much damage it has dealt and how many buffs it has granted. Buffs include: Lethal Tempo's attack speed, Fleet Footwork's Haste, Press the Attack's Vulnerable, Conqueror's Enrage, Hail of Blades' attack speed, Predator's Haste, Phase Rush's Haste, Summon Aery's shield, Aftershock's resistances, or Glacial Augment's slow.
- Increased chance to be given Predator when not near enemy champions, and less likely to get it when in combat with nearby enemy champions.
- Increased chance to be given Dark Harvest when near low health enemy champions.
- Increased chance to be given Hail of Blades when near low health enemy champions and building attack speed or attack damage.
- Increased chance to be given Conqueror when both you and enemies have high health, further increased chance for melee champions.
- Increased chance to be given Fleet Footwork if you are low health and below level 9.
- Increased chance to be given Glacial Augment if you have a Glacial item off cooldown.
- Increased chance to be given Summon Aery when you have healing/shielding power and are near a low health ally who is in combat.
- V9.23 - November 21st Hotfix
- Cooldown for melee champions reduced to 7 − 3 (based on level) seconds from 8 − 4 (based on level).
- Cooldown for ranged champions reduced to 11 − 7 (based on level) seconds from 12 − 8 (based on level).
- V9.23 - Added
- Replaces Kleptomancy.
- Inspiration Keystone rune.
- Periodically gain a single use of another random keystone. Once a keystone is rolled, it can't be rolled again until only three options are left, at which point the table resets (you won't get the keystone you just used, though).
- Gain a new keystone 8 − 4 (based on level) seconds after using the last. (Increased to 12 − 8 (based on level) seconds for ranged champions).
- Gain a new keystone while out of combat after 40 seconds of not using a keystone.
- Your current keystone shows up to the right of your health bar. All ten players can see it.
- Dark Harvest souls persist after you get a different keystone and affect all your other keystones. Grasp of the Undying's health persists after you get a different keystone, too.
- Available Keystones: Press the Attack, Lethal Tempo, Fleet Footwork, Conqueror, Summon Aery, Arcane Comet, Phase Rush, Electrocute, Predator, Dark Harvest, Hail of Blades, Grasp of the Undying, Aftershock, and Glacial Augment.
- Predator is only available to champions who have already purchased boots. Dark Harvest souls amplify the effects of all keystones. Aftershock is only available to champions who have learned a basic spell that can trigger it.
- Does not re-roll if in-combat.
- Keystones cycle pseudo randomly - you cannot repeat a keystone for 5 rolls after it has been used.
- Entering the fountain will reroll your current keystone.
References
 Precision
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 Domination
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 Sorcery
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 Resolve
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 Inspiration
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 Removed
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