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Mostly found in 
Zaun, where chemical research is unfettered by restrictions of law, Chemical Alterations can be found in abundance. Many Zaunites were chemically altered later in their lives, giving them superhuman abilities. These abilities can be one or more of the following: superhuman strength, superhuman speed, heightened senses, etc. However, unlike magical alterations, there are some glaring flaws in this kind of alteration, mainly tolls taken on one's mental state. Other symptoms can range from one's skin color changing to the loss of hair.
Lore[]
Chemically Altered Champions[]
Culture[]
Some of these chemicals are also illegally sold as drugs. An unlawful synthesis called "Shimmer" by Zaun's rebellious youth is a corrosive techmaturgical waste substance which stimulates intense emotions in its subject when applied by injecting, inhaling or consuming; taking Shimmer for a long time can lead to super strength, increased speed, and wound regeneration. Though frequent application of the caustic glop can result in progressive degeneration of the skin and muscle tissue. If lots and lots of Shimmer is used, one who is about to die from wounds could even be saved (but would have permanent changes to their body), such as when 
Jinx is injected with Shimmer and regenerates after a serious injury.
Sapient Species| Main Sapient Species |
Ascended · Brackern · Celestial · Dragon · Golem · Human · Minotaur · Spirit · Titan† · Troll · Undead · Vastaya · Vastayashai'rei† · Voidborn · Watcher · Yeti | |
|---|---|---|
| Lesser Sapient Species |
Azurite Eagle · Bubble Bear · Cat · Chirean · Coral Creature · Dredge Dredger · Fish Folk · Molediver · Pengu · Plague Rat · Poro · Shellshocker · Squill · Vellox · Whump | |
| Sapient Sub-Species | ||
| Ascended |
Aspect Host · Baccai · Darkin · God-Warrior | |
| Celestial | ||
| Dragon | ||
| Golem | ||
| Spirit |
Demon · Faerie · Fae Fawn · Luonn Kon · Naga · Nixie · Spirit God · Treant · Yordle | |
| Undead | ||
| Vastaya |
Besheb · Canghapi · Chyra · Fauhwoon · Juloah · Lhotlan · Khonlui · Kepthalla · Kiilash · Makara · Marai · Ophelis · Ottrani · Oovi-Kat · Raylu · Shimon · Skard · Sodjoko · Strig · Vesani · Vlotah | |
Sentient Species
Non-Sentient Species| Non-Sentient Species |
Blast Cone · Blue Stargazer · Calasa · Cavernberry · Citrus · Daisy · Duskpetal · Freljordian Grain · Grass · Honeyfruit · Kiwa · Lilie · Lotus · Medicila Elasticas · Mushroom · Naap · Night-Blooming Zychid · Nightbloom · Nirpooti · Parethan Corpse Tulip · Pearl of the Moon · Petricite Tree · Poppy · Raikkon Berry · Rose · Scryer's Bloom · Serpentleaf · Spirit · Sun Apple Tree · Tola Vine · Vlonqo Flower · Xaolan Tree | |
|---|---|---|
| Non-Sentient Sub-Species | ||
| Citrus |
Bilge Bitter · Demacian Tangor · Ionian Citrus Fruit · Noxian Orange · Piltover Shaddock · Shadow Citrus | |
| Lilie | ||
| Mushroom | ||
| Spirit | ||
Alternate Universe Only Species| Sentient Species |
Bantha · Chicken · Firelight · Forest Chameleon · Manatee · Porowl · Yonkeies · Unnamed Species |
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Other Species| Mentioned Species |
These species were only mentioned, but were never elaborated on. |
|---|---|
| Species Alterations |
These alterations are characteristics that multiple different species can have. |