Talk:Ryze/@comment-118.208.40.91-20120722122456/@comment-108.246.216.118-20120729204956

Actually, I've found that the best combo for Ryze is

Q R E Q W Q

Popping your ult right after launching your Q will allow you to do some AoE dmg as well as lowering the cooldown of Q by 1 second. Following up with a E lowers enemy MR and reduces the cooldown of Q by another second, leaving you ready to launch another Q. After this, you can cast your W and then wait one more second for one last Q.

IMO its his burst/nuke combo, but leaves him a bit defensless.