Talk:Kayle/@comment-131.252.4.4-20120604235115/@comment-2124153-20120607162501

Runes are pretty flexible, although flat Armor Seals are basically required. I prefer to run AS Marks, Vampirism Quints, and scaling MR Glyphs. It is possible to run other runes, though. A full AS page + Armor Seals works pretty well for clear speed and offense, at the cost of sustain and lategame durability.

I only run either 21/9/0 or 15/15/0 for masteries, and I prefer the second. An offensive mastery set allows you to get good clear times and DPS, a defensive one gives you some useful versatility (less damage taken, and access to scaling CDR).