User blog comment:Hyperion602/DotA 2 Style Lane Setups/@comment-5514182-20131214183906

This actually might work, if anyone could get a premade and try it out.

An example here is Twitch, Taric, and Janna bot; Nasus top; and Karthus Mid.

In the lategame, Karthus and Nasus engage on the enemy team. They are both very tanky and have decent damage, going for the enemy carries. Meanwhile, the bot lane champions go in a group behind the other two, fending off any assassins who get past the frontline and destroying the enemy tank.