Talk:Karthus/@comment-4499945-20120318013736/@comment-4184629-20120322064152

R>Q>E>W making sure to get all skills in the first three levels Q into E into W. Don't use E early game at all unless you absolutely have to (i.e, they jump you and you need bonus damage output, even then use it for a minor amount of time) like was mentioned save W for an escape or if you are going to do some major harass or the kill (sometimes if I am doing well enough and have harassed them horribly after a wall previously, I will zone them by placing the wall to scare the crap out of them, only do this if you feel you are trying to win the mental game and you are certain a jungle gank isn't imminent)