User blog comment:EggInABasket/Eggs Opinion on Smart Cast/@comment-4834593-20120508193953

I guess smartcasting is why LeBlanc always misses her Etheral Chains or whatever they are called when I play with/against them... They just click everything too fast.

I myself would say - use it for champions you know well, don't use it for champions you don't know well. And with line skillshots I'd say, never use it. You will not be able to exactly remember the range. However, targeted (like LeBlanc Q, Veigar Q, Annie Q, whatever), it could be a good idea to use it. Same for cones that stick to your champion (like, IIRC (and I just played him, so I think I do) Talon W, but not Annie W).