User blog comment:Lokiwg/Runes Lets talk about them!/@comment-24947613-20140904022447

All primary runes are efficient, if u know what yore doing;)

I rarerly go for "full smth" runepages, always combining like "5%crit 11AD" for Yasuo, "9%AS 11AD" for Tristy. As for seals and glyphs - similar case, combination of flat and scaling.