Talk:Kayle/@comment-122.107.77.122-20120526230028/@comment-2124153-20120530162551

On-hit is not really that much better earlygame, because even the cheapest ones are still investments. Since your items are your best bet for staying ahead of the curve, investing in on-hit means that you are betting everything on winning the game early. It's not at all like runes (which you build for power when items don't exist) or Doran's (which are built because they are the most cost-effective items).

Even still, some scaling runes make sense, like scaling MR on a jungler. They don't face magic damage in the jungle, so they use their Glyphs for late-game defense, since they have low salaires to begin with and could use the itemization assistance.