Talk:Rune/@comment-79.184.176.160-20120405011153/@comment-4089515-20120405011739

My advice, which is probably the same as most people will give you, is to not buy any runes until you hit level 20, where you can buy tier 3 runes.

In answer to your questions, once you buy a rune, you're stuck with it. You can combine some with Rune Combiner (but that's random and bad). You can remove runes from your page, but you still have those runes if you want to use them later. As for the SPECIFIC runes, I don't play LeBlanc, so i'll let someone who does fill you in on that.