User blog comment:StrategicMagic/Vayne - Carry? Yes. AD? No./@comment-5266525-20120819110651/@comment-5266525-20120819145539

^^ I meant countering in the sense of reducing the damage it deals per hit. But overreliance on her W will probably get her hard-countered by those two items. And Malphite. That's part of why it's likely a bad idea.

^ Does she not? Last Whisper is a ridiculously common item on all AD carries, including Vayne. Madred's Vayne would be wasting a lot of potential to build, say, Sorc Shoes just to make Madred's damage meaningful.