Talk:Karthus/@comment-38258081-20190223184448/@comment-37514365-20190309042353

Runes: Dark Harvest-for a late game karthus or Aery-for more consistent poking

Manaflow Band-obviously to solve mana problems

Transcendence-for more AP and CDR Scorch-to improve poking

Precision Second tree Presence of Mind-very important on karthus! gain mana and CDR each kill

Last Stand-last stand improves Karthus' damage during his passive

about items, though. i don't know much. you can either get Rod of Ages first item for survivability and damage or Archangel's first to solve mana issues.