User blog comment:NowItsAParty/Truly Ascended/@comment-5593561-20140911224313

Staying together is the best strategy, it's harder to kill your team's Ascended if the team moves together and enemy team won't get the first Ascended either when half of your team didn't die while soloing on relics. Relics can also be taken faster with multiple people.

Bruisers, assassins and substain champions are most useful, but the best champion is clearly Teemo, because the enemies have to constantly move around the map they will eventually step on your shrooms no matter where you place them. Ascended buff also scales well for him. And best part? You can troll the shit outta them because it doesn't respawn as long as you are alive.