User blog comment:Ozuar/The Importance of Skill Order in League of Legends/@comment-68.54.8.85-20130329114139

I think that the role is what decides your spells. For instance, I happen to play Elise in top, mid, and jungle and sometimes support. She's intensly flexible, almost rivaling Pokemon Trainer from Super Smash Brothers Brawl. When in top lane you start with her Neurotoxin (Q) because the people in top tend to have high hp and the hp crush on Neurotoxin HURTS and in spider form it hurts even more. If someone is dumb enough Elise can draw first blood with Q alone.

While mid is a different story. A lot of mages have more range and damage to accompany that range, so she goes with her Volitle Spiderling (W) because it makes up for her lack of range by throwing out a homing double its range bomb. In spider mode by level 3-6 shes ready to engage the enemy by dealing fast damage and sustaining through the pain of close combat thanks to the spellvamp.

Jungling requires Elise to take her W for the spell vamp then grab her q for the hp crush, then grab her E for the stun and ganks and shes ready to go.

With the support role however, starting with her stun is the best choice to aid your carry in kills. Then as you level up start getting your burst ready because if you tdo it correctly you can take out 1/4 to half the enemy carries health and then your adc can help finish thecarry off.

What I'm trying to say here is spell orders are important and in a way, a necessity.