User blog comment:StrategicMagic/Vayne - Carry? Yes. AD? No./@comment-3275908-20120821010611/@comment-3275908-20120821022411

@Vahldeer: You sir are a good man and you bring up a valid point. It is probably best to go with boots + pots at the beginning (which is the more than typical start for any position) instead of a dagger as it brings more sustain and maneuverability.

Also, I should bring up the quality of your support partner in the lane if you are building AS/on-hit Vayne. For example, Nunu works well for the MS and AS and could be a prime candidate. Leona may also work well for the extra burst and her lockdown CC. As for others, Alistar can protect + lockdown, and Nidalee can heal + give AS. Depends on your partner's cup o' tea.