Dr. Mundo/Strategy

Skill usage

 * can stay in lane very long since he is manaless and his allows him to regenerate Health very quickly.
 * Practice with and other skill shots will often land extra kills when chasing enemies. Missing will often cost the enemy's escape.
 * is very effective in taking out neutral camps. It deals damage based on enemy health and neutral creeps tend to have large amounts of it. This allows to jungle effectively.
 * Because makes a distinctive splat noise when it hits an enemy, it can be used reliably for checking bushes for enemies.
 * deals 1 tick of damage immediately upon usage, allowing easier lasthits.
 * Since also gives you crowd control reduction in addition to the damage, don't forget to use it during team fights or while chasing/fleeing especially against crowd control heavy enemies. Also, the reduction does stack with  to make crowd control very ineffective against.
 * Effects that reduce healing can greatly decrease survivability. Try to wait until after you've seen them use it before casting.
 * A well-timed can bait enemy champions into attacking you even when they lack the damage to finish you.
 * After you reach level 6, you should very rarely have to leave your lane. has a fairly short cooldown and because  abilities use health, this allows you to regain most lost health every minute or so.
 * continues to heal you when you're resurrecting from . Timing a well with  is a very good way to bait and finish off low health opponents who wait for you to resurrect.
 * ,, and make  an amazing chaser who can chase champions all the way back to their spawning pools for kills.

Build usage

 * should be a core item no matter what you're building, as its 15% boost to regenerative effects works on, effectively changing its regen from 40/55/70% to 46/63.25/80.5% and giving cooldown reduction. will also increase the health return from 's effect.
 * Be careful of buying too many health items like or  if the enemy team has one or more champions who can make use of  or if they have a  as his  can make quick work of you.
 * Stacking health and getting an can greatly boost your damage, as well as increasing your survivability.
 * Attack speed items ( / ) greatly increase damage output with.
 * is also an excellent item on . It gives him extra health and the guaranteed slow. The slow from mallet stacks with the slow from, giving him exceptional sticking power on enemies.
 * and synergize well with.
 * Magic Penetration is generally more useful to than ability power.  gains no benefit from ability power as its damage is based on enemy health, but still deals magic damage.
 * Grabbing a is useful for countering healing reduction debuffs like.
 * With a maxed out, a , and a , Dr. Mundo can go where he pleases with activated as his health regeneration cancels out the cost.

Countering

 * Debuffs from and  can be an extremely effective counter to  and weaken his regeneration tremendously. If playing against a good  one of these two should always be available in team battles.
 * is also effectively countered by champions with healing reduction abilities, such as, , and.
 * If is stacking health items, especially, then  would be a wise item to build.