Talk:Vladimir/@comment-5159141-20120927134143/@comment-4659726-20121011034058

You adapt to the lane you are fighting against, although Vlad's runepages are fairly simplistic.

Magic pen Marks are the only locked in item.

Hp/lvl seals or armor seals, both are good for duariblity and armor is used for really tough AD heavy lanes. Hp/lvl is useful for scaling better with levels in terms of durability and surviving other types of damage such as magic and true damage. And definitely is worth a look against some top lanes when Doran's shield/chain vest/maybe even tabi make up most of your armor needs as Vlad.

Glyphs are really really interesting, there are the two AP glyph types of per level and flat. Both of which are useful on Vlad to either scale with levels or gain an early game advantage. Then there is flat CDR glyphs which give Vlad better early cooldowns while having more effective CDR later in the game. Then there is flat mr (I don't list scaling because vlad needs early durability). Flat Mr is great on midlane Vlad if you go offensive masteries as it gives you the durability you need for your laning.

Quints: Spellvamp does scale but I find that the benefit it gives you early game is minimal. While you can certainly take spellvamp, I am not sure I could reccomend it after playing around with them and comparing to other Quints.

Even more so when other Quints work extremely well. Movespeed works for Vlad's short ranges allowing him to kite in and out of fights easier and be overall more "safe", as well as giving him a bit of slipperyness to his playstyle. AP works for an early boost in damage although that is all they give.

Overall, going in with the same runepage all the time is not the best idea, though because there is a good amount of overlap in good runes Vlad can get away with less runepages than other champions. 3 Being the max amount I can think of.