Talk:Vayne/@comment-4442345-20120710202027/@comment-4743916-20120721080705

The reason why those people may run 9 in utility instead of defense is because A. Utility scales toward mid and lategame while defense only assists in laning phase and B. Mana regen for the amount of points you use is more efficient as they give you essentially 6 mana regen runes for the cost of 3 mastery points while most of the earlier defense tree masteries are worth about 1-1.5 runes for each point used.