Talk:Ryze/@comment-66.234.208.72-20111113225232/@comment-1748472-20111117205622

Most commonly Q comes first but if you judge every situation for itself the rotation can start with pretty much any of his skills.

Q if you want a fast rotation with huge burst and minimal CD. W if you want to make sure the target doesn't escape (if it's on the run already e.g.) while you finish your rotation. E if you want to apply the magic resistance-debuff to multiple enemies for your team mates to immediately deal more damage.