Talk:Karthus/@comment-31.205.49.67-20120204172135/@comment-4562912-20120204220925

You can dodge it using some abilities (like vlad's pool) or Zhonya's Hourglass' active. Some AD players like Hexdrinker for the magic resist and shield. Otherwise any MR item to mitigate the damage. Guardian Angel can revive you. You can keep Elixir of Fortitude (red potion) in your inventory and drink it in case you need the hp boost to survive. The new shield item might work, too.

Or just pick Soraka.