Talk:Manamune/@comment-24823977-20141001140754/@comment-10428734-20141008210938

It would probably be overkill, especially if played assassin-style. Assassins are too snowball-dependent to delay their core damage items too much: you need to be killing people mid game, not to be stacking a tear. Furthermore, Wu has no real synergy with Muramana's toggle and I don't see Manamune replacing any item of your build.

TF > Manamune because of Q + Spellblade is your core damage. Hydra > Manamune because of the lifesteal (Wu lacks any kind of innate sustain). Cleaver > Manamune because of armor reduction (further increases damage from your ADC, stacks very well with Q). Maw > Manamune because otherwise you would be too easy to burst down.

Don't know much about FM (IMO Randuin and GA are just always better). Though if you replaced it with Manamune, you would definitely be waaaaay too squishy late game.

Honestly the only legit Manamune users are Urgot/Yorick/Jayce (maybe Warwick?). No other AD champion even needs half the mana sustain it gives.