User blog comment:Hyperion602/DotA 2 Style Lane Setups/@comment-6000413-20131216140044/@comment-13944607-20131216172926

The only reason that I'd prefer to send the trilane bot rather than mid is because by its nature the trilane will shut down its opponents, just through having the numbers advantage. It's much more effective to shut down the bot lane than the mid lane, mostly because there aren't a lot of mid laners who can carry to the extent an ADC could. There are a few exceptions, obviously, and in that scenario you can send the trilane mid. Keep in mind you ARE allowed to be fluid and lane swap depending on the situation.

As i said to the comment below, top being alone isn't a problem, because you pick someone who escapes ganks easily and is difficult to tower dive, and becomes strong without needing kills. Namely, champions such as Shen and Nasus.

Lastly, every part of the jungle would still be being used, albeit at slightly reduced efficiency, but its not being wasted. And while you can't deny minions in the sense of last hitting your own minion, like in DotA, you can deny a lot of farm through zoning with 2 supports being a constant threat. Also, my response to CarFox addresses the issue of securing buffs, warding, and the like.