User blog comment:Fistful of Force/AvS Pt 1: Annie Support Burst Potential/@comment-3308937-20131124220409

No carry goes without mres blues so it'd be 42 mres. With mpen reds that means her burst would do 375 damage with 1 tick of tibbers, about 400 when you factor in AP from runes.

A Vayne would have 937 health, factoring in Doran's Blade. This'll bring her to 537 or 58%, Soraka's W would bring that back up to 758 or 81% health, if ignited then it would bring her back up to 648 health or 69%. Soraka could then just silence Annie and her and Vayne can disengage and get back to farming.