Talk:Zed/@comment-27722295-20160418182110/@comment-4091261-20160421184231

You are definitely going to lose early game damage output going anything other than. One great suggestion I have using a glyph. This gives you higher burst potential than other enemies throughout the game without sacrificing damage output through your build or runes. This grants an edge against mirror match and other assassins you'll find dueling you.

If you find that you can't win early game no matter what you do, don't despair and just use marks while playing safe. These marks give you around the same as  marks when you are level 7 and net you a potential  more than  marks. Don't bother using quintessences though. They only net you over  quintessences, which isn't significant enough to offset the early game weakness.

There isn't a reason to limit yourself at 10 armor penetration. The lowest you will see from a champion early game is 16. Even then if you rush at level 6 against the second lowest armor character,, the armor pen you would need to be efficient is 7.24. Though this doesn't really matter because the whole point of armor penetration is to have such overwhelming damage against the enemy that even getting wouldn't be enough to stop it.

The whole point of getting penetration at all is to force the enemy to go out of their way to build a when the enemy has no synergy with tankiness. So technically you can use a full armor pen rune set against any champion you suspect would rush a against you.

So in the end, gives the highest early game damage output. You can further amp your damage output with a   glyph. marks are good for if you aren't really good early game in that mirror match and allow you to scale over the enemy eventually, but don't use  quintessences. For armor penetration, don't bother going any less than 19 armor penetration because is best in almost every situation other than if the enemy rushes.