User blog comment:YourPrivateNightmare/A discussion about Runes/@comment-5955640-20150915235047/@comment-4091261-20150922112618

Only thing I find troublesome about that is if the runes in particular don't help the current champions used. Like for example, AP runes when Vayne is the only champion bought so far. Or more notably any quints that don't help the current champions used. This is of particular annoyance as some full sets of quints cost 6,150 IP which may be more expensive than the actual champion.

One scenario would be buying movement speed quints for. This is where there is some scrutiny in choices, by default buying runes first is a good idea, but when champions' cost don't compare to the runes' cost, then it's questionable.