Talk:Warwick/@comment-17738098-20140519162055/@comment-4022742-20140520031923

I personally use a custom mixed rune set made for Warwick specifically tailored to go along side the mastery page I have for him, so I run the awkward set up of:
 * 9×Greater Mark of Hybrid Penetration.
 * 8×Greater Seal of Scaling Health.
 * 1×Greater Seal of Percent Health.
 * 9×Greater Glyph of Cooldown Reduction.
 * 2×Greater Quintessence of Movement Speed.
 * 1×Greater Quintessence of Percent Health.

Then switching to masteries, I run 9/21/0 with another quirky set up: With this set up you'll get some nice even stats that will benefit you the entire game, if you feel like you survive the jungle easy, you could get Enchanted Armor over Recovery to get more benefit from your armor mid/late game. In total it works out to give: +10% Cooldown Reduction... +5% Max Health... +3.75% Attack Speed... +3% Movement Speed... +8 Armor Penetration... +5.5 Magic Penetration... +128 Health@18... +14 Attack Damage@18... +5 Armor... +5 Magic Resistance... 2 Damage reduction vs Champions and Monsters... 10% Critical Strike damage reduction... 4% Area of Effect damage reduction... and 15% Crowd Control duration reduction.
 * Offense
 * 2×Sorcery
 * 3×Fury
 * 3×Brute Force
 * 1×Martial Mastery
 * Defense
 * 2×Tough Skin
 * 1×Bladed Armor
 * 2×Recovery
 * 2×Block
 * 1×Unyielding
 * 3×Veteran Scars
 * 1×Juggernaut
 * 3×Hardiness
 * 1×Reinforced Armor
 * 3×Resistance
 * 1×Evasive
 * 1×Tenacious

As for Items I usually rush, and ... Building parts of  and  if I happen to take a lot of damage of a specific kind. And I finish with a situational CDR item, usually to round out my "Buff the Team" build, giving AS, MR, HP regen, AD and LS aura's.