Talk:Karthus/@comment-4636093-20130615142223/@comment-4636093-20130615203801

As soon as you toggle Defile on, its 'first tick' ticks for damage.

It then ticks once every second for more damage.

However you can rapidly spam your E key and toggle it off then on again, making it deal that instant 'first tick' multiple times in under a second.

http://www.youtube.com/watch?v=E5SiP6ORPLA Watch @ about 2:53:40. Link on Karthus uses it while rushing Baron, and Phreak commentated on the technique.