Dr. Mundo/Strategy

Skill usage

 * can stay in lane very long since he is manaless and his allows him to constantly regenerate health.
 * is very effective in taking out neutral camps. It deals damage based on enemy health, which neutral creeps tend to have a lot of. This allows to jungle effectively.
 * Because makes a distinctive splat noise and returns health when it hits an enemy, it can be used reliably for checking bushes for enemies.
 * deals 1 tick of damage immediately upon usage, allowing easier last hits.
 * Since also gives you crowd control reduction in addition to the damage, don't forget to use it during team fights or while chasing/fleeing especially against crowd control heavy enemies. Also, the reduction does stack with  to make crowd control very ineffective against.
 * Effects that reduce healing can greatly decrease survivability. Try to wait until after you've seen them use it before casting.
 * A well-timed can bait enemy champions into attacking you even when they lack the damage to finish you.
 * After you reach level 6, you should rarely have to leave your lane. has a fairly short cooldown and because  abilities use health, you can regain lost health about once every minute.
 * continues to heal you when you're resurrecting from . Timing a well with  is a very good way to bait and finish off low health opponents who wait for you to resurrect.
 * Due to a tendency for many players to counteract Dr. Mundo's health regeneration with, taking as a summoner spell might seem like a good choice; however, it does not actually remove the healing debuff, only the DoT. It does combine well with  to cause strong crowd control resistance, though.
 * ,, and make  an amazing chaser who can chase champions all the way back to their spawning pools for kills.
 * Since is a regeneration buff and not a heal it will give you the most survivability if activated right before you take major damage

Build usage

 * is a very effective item for Mundo due to its 15% boost to regenerative effects, cooldown reduction, and extra tankiness, all of which benefit
 * However, the regeneration and pure health of is usually better than . Only get, if you use a build that relies on cooldown reduction or need that extra magic resistance.
 * Be wary of buying too many health items like or  if the enemy team has a  or a, as both will can make quick work of your health.
 * However, both counters lose their effectiveness if you build magic resistance. Mundo with, , and will have around 150 magic resistance, meaning Madreds procs will only damage you for about 1% of your max health instead of 4%.
 * should be considered as main early/mid game item due to possibility of building it into few cheap and very useful items like, and  which together give impressive 40% cooldown reduction, boost his passive thanks to additional hp, and improve survivability and dmg output of  and surrounding allies with lifesteal, attack speed and short speed boost.
 * Stacking health and getting an can greatly boost your damage, synergizing with, as well as increasing your survivability.
 * Attack speed items or critical chance items ( / ) greatly increase damage output with.
 * is also an excellent item on . It gives him extra health and the guaranteed slow. The slow from mallet stacks with the slow from, making him incredibly effective at keeping an enemy locked down with constant slows.
 * and stack favorably with.
 * Magic Penetration is overall more useful to than ability power, because  gains no benefit from ability power since its damage is based on enemy health, but still deals magic damage.
 * Grabbing a is useful for countering healing reduction debuffs like.
 * With a maxed out, a , and a , Mundo's health regen will outpace the health cost of.
 * Due to his high base Attack Damage(110) and his low Cooldown on and,  can use the proc of / very effectively.

Countering

 * Debuffs from and  can be an extremely effective counter to  and weaken his regeneration tremendously. If playing against a good  one of these two should always be available in team battles.
 * is also effectively countered by champions with healing reduction abilities, such as, , , and.
 * If is stacking health items, especially, then  would be a wise item to build.
 * Don't stack health when facing, as it increases his damage from.