Talk:Vayne/@comment-122.3.169.11-20120617104648/@comment-88.102.160.74-20120617210521

Just like with any other AD carry. Marks, seals and glyhps are set in the stone (flat AD marks, flat armor seals, mres/level glyphs) and taking anything else is completely retarded and unviable.

Quints offer a bit more freedom of choice, although flat ADs are superior to others. You can take for example speed quints if you wanna be faster, life steal if you need more sustain, flat health or flat armor for early game durability or flat mres if you REALLY hate mages. All these options are somewhat useful but still not as good as flat AD.