Talk:Lissandra/@comment-26878675-20160127225640/@comment-25904283-20160130043906

Liss has early mana problem, but that is relieved quickly after 1st back (when you buy either Catalyst, parts of a mana regen/CDR item or even another Doran). Thus, mana rune is pretty much useless after. Same goes with Meditation on her. You basically change the rune set and mastery to something sub-optimal just to use Corrupting Potion, which is not a good sign in term of efficiency.

Another point is Doran gives AP which help with both poking the enemy champion and clearing waves, while Potion only works against champion.

Not that Potion can't work, but most of the case Doran is better.